New York Blood Center
Thursday, June 16th 11:30 - 12:00 UTC+2
Thursday, June 16th 11:30 - 13:00 UTC+2
My research interests during a research career spanning 50 years have largely focused on studying red cell function in health and disease in order to better define the mechanistic basis for the contribution of decreased red cell life span to anemia in various red cell disorders. A major feature of research efforts during my entire research career has been the ability to effectively interact with large numbers of talented investigators nationally and internationally attested by my publication record of 420 peer-reviewed articles many of which are the result of these collaborative efforts. Current research efforts include studying red cell membrane biogenesis and erythropoiesis in health and disease including sickle cell disease. Specifically, the research efforts include defining the contributions of reduced cellular deformability to increased red cell destruction in various human hemolytic disorders involving membrane abnormalities, sickle cell disease and malaria.